Wales full back Lee Byrne has lost his battle to help the Ospreys face Munster in the Heineken Cup quarter-finals this weekend.
Byrne failed a fitness test in the Welsh region's final training session today and has been ruled out of Sunday's sell-out clash in Limerick.
Byrne damaged ligaments in his left foot during the Six Nations clash between Wales and Ireland and has not played since. He hopes to be available to play again within a few weeks.
Also missing from the Ospreys line-up is another of their British & Irish Lions contenders, Gavin Henson. He is now two weeks into his recuperation after twisting his ankle in the EDF Energy Cup semi-final defeat to Gloucester.
That caused damage to his ligaments on both the lateral and medial sides of his right ankle and he is likely to be sidelined for at least another month.
As part of the build-up to next month's Cardiff 2014 Heineken Cup and Amlin Challenge Cup finals weekend, ERC has joined forces with the WRU, Cardiff Blues and adidas to develop an annual grassroots community rugby programme targeting young players.
The Ulster Rugby full back, Jared Payne (No 15), has been suspended for two (2) weeks following an independent Disciplinary Hearing in Dublin arising from the Heineken Cup quarter-final match against Saracens at Ravenhill Stadium on Saturday, 5 April.