Northampton Saints, Munster, Scarlets and Ulster have all been to Stade Pierre Antoine and won in recent seasons, although the Saints and Ospreys have both been despatched in close encounters so far this winter. But the man behind those two victories, Rory Kockott, is missing this weekend and that could be a huge advantage for Leinster.
Kockott kicked 14 of his side's 19 points in the 19-13 first round win over the Saints and then 12 of the 15 in the 15-9 victory against the Ospreys. His boot will be missing and Leinster's experience could tip the balance.
"The guys have been to France a lot. There is a lot of provincial and Test experience of playing in France," said O'Connor.
"You have got to get your head around it. You have got to understand what you have to deliver on across the course of the contest. A lot of those things are really hard physical things. But, if you can match them there, you're in with a chance."
The game will see Rob Kearney join the 'ERC Elite 50' club when he makes his 50th appearance in the tournament.