Head coach Lyn Howells admits the nature of that opening round defeat was hard to take but he insists there was plenty to be positive about in their Amlin Challenge Cup opener.
"We have never beaten an English team and I really thought this was going to be it," said Howells, who coached in the Heineken Cup with Cardiff and the Celtic Warriors and also took Pontypridd to the Amlin Challenge Cup Final back in 2002.
"It was pretty cruel in the end because we should have won and I don't think many would have argued with that. We just lacked a bit of experience in the final few minutes to close out the game.
"But overall I was so pleased with the players, they gave everything and deserved more against a team that included six regular first-team players from the Premiership. And they had to bring on another four off the bench to get the win.
"It was very pleasing from a national point of view as well. I was looking for another option at No10 so we played our scrum-half there and he went really well. It has given me another option for Bucharest and Romania."
Defeat may have left Bucharest at the bottom of Pool 3 after Calvisano held former Heineken Cup kings Brive to a draw in Italy but Howells still feels his side can push for a quarter-final spot if they can beat the Italians next time out.
And given that they were victorious in the same fixture last season - a campaign in which they also beat French outfit Agen - the Welshman is confident his side can make the most of the early home advantage handed to them as a result of the harsh Romanian winter.
"It's a game that we have to target for a win," added Howells.
"We beat them last season but they have obviously improved a lot after taking Brive all the way last week. We have three home games in a row and we want to get a couple of wins under our belt.
"This pool is wide open. We should have beaten Newcastle but they will have to concentrate on staying up in the Aviva Premiership and Brive will have to focus on the Top 14, so there is a big opportunity for either ourselves or Calvisano to push for top spot. The next game could have a big baring on that."