But his impressive performances for his club in Pool 6 of the Heineken Cup - where they are within touching distance of quarter-final qualification - and the Top 14 have earned him a place as one of four centres and will battle for a place with incumbent starters Florian Fritz and Maxime Mermoz as well as Toulouse's Gael Fickou.
The 33-man group is headed up by new captain Pascal Pape.
The Stade Francais second-rower takes over the reins from Thierry Dusautoir, who has been included in the squad after missing the autumn internationals with a knee injury but will be spared the extra responsibility of the leadership.
Dusautoir forms part of a formidable group of back-row players, with Saint-Andre also able to call on Yannick Nyanga, Louis Picamoles, Fulgence Ouedraogo, Damien Chouly and Wenceslas Lauret.
Medard, like Dusautoir, is on his way back from injury and though he was offered hope for the future, he will have to wait for a recall after missing much of last year with knee ligament damage.