They lead Pool 1 by two points ahead of Racing Metro 92 and the Round 5 clash between the clubs at Stade de la Beaujoire in Nantes on Saturday, 12 January, could be decisive in the chase for group honours and automatic qualification.
Saracens, now lying second in the Premiership after defeating Northampton Saints 17-16 at the weekend, won the Round 2 encounter against the French club 30-13 back in October and would put themselves firmly in pole position with a fourth win from five starts.
Burger, who made the last of his eight tournament appearances against the Ospreys 12 months ago, battled through the pain barrier to be named one of the five best players of the 2011 World Cup, just a few months after being voted Saracens player of the year when they won the Premiership title.
He had a clean-up operation in January 2012, but it quickly became clear that he would need something more permanent.
"I will go through almost anything just to get the satisfaction of playing," said Burger. "Looking back I probably shouldn't have played in the World Cup but it was always going to be huge and how often do you get the opportunity to captain your country at an event like that?
"In those big games you can live with the pain because after about 10 minutes everything else was hurting so it was just part of the picture. But on a day-to-day basis there was no way I could continue."