His last appearance for the national side was in June of this year against the USA in Houston, a week after he scored his only international try against Canada in Toronto.
Discussing the signing, Director of Rugby Nigel Davies, spoke of the reasons behind D'Apice joining: "Tommaso has been on trial here for just over a month now. He's an international hooker who has played for Italy in the Six Nations and in the World Cup".
"He's committed a lot to coming here. He could probably have gone to other clubs for a lot more money but wanted to be part of this Gloucester team and we're delighted to have him on board."
Gloucester kick off their Amlin Challenge Cup campaign with a demanding Pool 1 away game at Mont-de-Marsan on Thursday, 11 October.