If they manage to emulate Leicester Tigers' achievement in 2001 and 2002, Leinster will also be lifting the coveted trophy for an unprecedented third time in four seasons while Ulster will be bridging a 13-year gap since their famous final victory in Dublin in 1999.
As the countdown to Saturday week's much-anticipated clash begins, this will be the fourth time that Twickenham Stadium has hosted the final, and on each previous occasion an English club has emerged victorious. Northampton Saints edged out Munster Rugby in 2000, and then in 2004 and 2007, London Wasps were successful beating Toulouse 27-20 and Leicester Tigers 25-9.
With an expected sell-out crowd of 82,000 packing Twickenham, the Heineken Cup will be the showpiece event of ERC's London finals weekend which kicks off with the Amlin Challenge Cup final between Biarritz Olympique and RC Toulon on Friday, 18 May.
Friday, 18 May
Amlin Challenge Cup final
Biarritz Olympique v RC Toulon - Twickenham Stoop (20.00)
Saturday, 19 May
Heineken Cup final
Leinster Rugby v Ulster Rugby - Twickenham Stadium (17.00)