"This is a big one for us because, although we have qualified for the knock-out stages, we have not yet got the home quarter-final we want," said full back Denis Hurley.
"We have to go to Northampton to get the win and a home quarter-final because playing at home is massively important for both our players and fans.
"And the Saints and ourselves know each other pretty well after playing three matches in the 2009/10 Heineken Cup - there is always great competition between what are two very good sides.
"They may not be able to qualify for the quarter-finals but we know they will come out fighting because they are a very proud club and there were only two points in it when we won at Thomond Park in Round 1.
"There has been some talk of us not playing well but still winning but I feel we have stood tall against all the teams we have played against and, at the end of it, winning games is the most important thing.
"We are in this strong position because we have won all five of our group games and when we click we are a very dangerous side.
"It means we have qualified for the Heineken Cup quarter-finals for the 13th time and that is a great record because we take enormous pride in our game."
Hurley could find himself going head-to-head with England star Ben Foden, who has been in outstanding form at No 15 for the Saints this season.
"Ben is in great form at the moment and it would be great to play against someone of his talents and really test myself," added Hurley.
"However, we are two completely different players and my focus will be entirely on making sure I do the basics right and, hopefully, that our back three can get across the gain line and test their defence.
"At the same time, our aim will be not to give them the space and room to attack us because we know just how dangerous they can be given that time and space."