The Top 14 side have swept all before them in their Pool and will be expected to record 'the double' over the Bucharest Wolves when the two sides clash at the Stadionul Arcul de Triumf.
Stade Francais Paris, who lost in last year's final to Harlequins, will be determined to keep their momentum in the tournament before their final game against the Warriors in Paris next weekend.
Worcester Warriors v Banca Monte Crociati
(Saturday January 14, KO 15:00)
Worcester Warriors will be determined to keep the pressure on Pool leaders, Stade Francais Paris, in Pool 1 when they host Italian minnows Banca Monte Crociati at Sixways Stadium
The English Premiership outfit have only lost one game in their Pool during this campaign and will be looking for a fourth victory against an Italian side yet to win in Europe this season.
The Warriors will want to rattle off a bonus point victory at home on Saturday ahead of their must-win clash with Stade Francais Paris in France in the final Pool game next weekend.
The final game between the top two sides in the Pool promises to be a cracker at the Stade Charlety and will decide which of the two sides will qualify for the knockout stages.