Sale are currently fifth in the English Premiership and come into the game on the back of an impressive victory away to Bath.
Similarly Agen are competing well in the French TOP14 having won their last four outings.
Rugby Club La Vila v Brive
(Saturday December 10)
European debutants Rugby Club La Vila welcome Pool leaders Brive to Spain on Saturday.
Brive won their opening two games in the tournament back in November and will be looking to stamp their authority on the Pool when they line up for the back-to-back games.
The French side have struggled in the TOP14 and are without a win since mid-October but with the likes of former England international Jamie Noon in their ranks they will be looking to put one foot into the quarter-finals.