Former All Blacks Joe Rokocoko, Neemia Tialata, Sione Lauaki and French international, Cedric Heymans, and Wallaby Mark Chisholm are just a few of the big names recruited by Bayonne in the summer.
Rovigo will be hoping their visitors are rusty after their Top 14 derby against Biarritz was postponed last weekend, and will be looking for only their second victory over French opposition in the tournament.
The Italian outfit's only previous victory over a French side in the Amlin Challenge Cup was against Dax, when they recorded a 24-11 victory, during the 2008/09 tournament.
Bordeaux-Begles v London Wasps
(Saturday November 12, KO 20.55)
Former Champions London Wasps face a tough opener to their Amlin Challenge Cup campaign when they travel to France to face Bordeaux-Begles at the Stade Andre Moga.
The English giants beat Bath 48-3 at the Madejski Stadium to lift the trophy in 2003 and lost to eventual tournament winners, the Cardiff Blues, in a home semi-final in High Wycombe in 2010.
New coach David Young, who was in charge of the Welsh side that day, will be looking to repeat his success with the Blues in this competition and restore his new club's European pedigree during this campaign.
The newly promoted Bordeaux-Begles will be hoping to re-establish their once fearsome reputation throughout Europe as the return to European competition for the first time since 2003.
The French outfit, who have been out in the rugby wilderness at home, were once a regular feature in European competition a decade ago and will be looking to prove they deserve to be back in top flight rugby