Director of Rugby Andy Key said: "Naturally we are all very excited about this game,. No matter who you are you want to test yourself against the very best and Stade are unquestionably - and regularly - one of the best sides in Europe."
Bucharest Oaks host Crociati Rugby at Acrul de Triumf.
The Romanians's will aim to gain victory in their opening home game of the competition and in the club's history.
Both teams will want to get out of the blocks after suffering defeat in the opening fixtures.