Sale were easy victors when they faced Worcester at Sixways back in October and there is nothing to suggest the outcome will be much different this time around.
Since that 29-15 win in Round 2, Sale have picked up a losing bonus point at Oyonnax and hammered the Top 14 newcomers 53-14 last time out. Their three most recent league games have seen the Sharks win at home to London Irish and away at Newcastle on Friday night and leave Leicester with a losing bonus-point the week before last.
It's a vastly different story for the Warriors, who are still without a win in the Amlin Challenge Cup or the Aviva Premiership, with their season so far featuring just a single success against Cardiff Blues in the LV= Cup.
Dean Ryan's men were beaten by London Irish on Saturday afternoon and have now lost all 12 Premiership fixtures, while they suffered more heartbreak on both of their most recent European outings as Biarritz robbed them of a maiden win late on both home and away.
They were on track for a morale-boosting win at Biarritz in Round 4 but failed to hang on to a healthy lead even when their hosts were down to 14 men, while they were beaten by a try with the final play in the reverse fixture in the Midlands.