Alun Wyn Jones has admitted his Ospreys side have been perennial underachievers in Europe - the Swansea-based outfit having only reached the knockout stages on three occasions and never gone beyond the quarter-finals.
But the Welsh region have made an impressive start to the season in the Pro12, only losing their unbeaten record with a slender defeat at the hands of Ulster at the Liberty Stadium last weekend, and they have already been to Dublin to face the reigning Amlin Challenge Cup champions and come away with a draw.
They boast a formidable pack, containing five summer tourists with the British & Irish Lions, and will have Dan Biggar pulling the strings at outside half. Expect a battle royal up front.
But Leinster, even without the injured Brian O'Driscoll, will be determined to prosper once again in Europe's top-tier tournament, having failed to reach the knock-out stages for the first time in five years last season.
They have stuttered at the beginning of their season, winning just two of their five league matches to date under new head coach Matt O'Connor. But they lay claim to an equally star-studded squad with seven former Lions within their ranks.
The two sides have never met in European competition, but they have shared a fierce rivalry in domestic action. Twice the Ospreys have conquered the Heineken Cup heavyweights in domestic Grand Finals.
When they clashed in round two of the Pro12 this season they shared a 29-29 draw at the Royal Dublin Showground. And Saturday night's showdown promises to be another thrilling encounter.
Saturday, 12 October 2013 Kick-off: 18:00 Liberty Stadium
Referee: Wayne Barnes (Eng)
Assistant Referee 1: Tim Wigglesworth (Eng) Assistant Referee 2: Paul Dix (Eng)
TMO: Geoff Warren (Eng) Citing Commissioner: Shaun Gallagher (Eng)
TV: Sky Sports, Sky Italia Ospreys are meeting Leinster in the Heineken Cup for the first time.
- The Welsh region have played Irish clubs on seven occasions in this tournament, winning three and losing four.
- Ospreys were undefeated in this tournament last term (W2 D1) at the Liberty Stadium.
- Leinster have won their last 11 Heineken Cup matches against Welsh regions.
- Despite failing to make it out of the pool stage, Leinster had the best tackle success rate (92%) in the Heineken Cup last season.
- Leinster averaged fewer kicks from hand (17.5) than any other side in the Heineken Cup in 2012/13.
- Only two players (Napolioni Nalaga and Wesley Fofana of Clermont) beat more defenders than Ospreys' Eli Walker last season (23).
- Justin Tipuric totalled nine turnovers for the Welsh club last season - only Rory Best of Ulster Rugby (14) secured more in the 2012/13 tournament.
- Leinster have lost just two of their last 10 away games in this competition (W7 D1) with both defeats coming at the hands of Clermont.
- Ospreys have lost just one of their last 22 home games in this tournament (W19 D2).