Fly-half Owen Farrell's boot and 11 from 11 shots at goal made sure Saracens recorded an impressive 37-28 over French rugby's big spenders Racing Metro in Nantes to put them in pole position in the Pool.
The English Premiership side will be confident they can beat Edinburgh and will fancy their chances of a getting the bonus point to help their chances of a home draw in the last eight.
Edinburgh, who reached the semi-finals of last season's Heineken Cup, have endured a miserable campaign and have yet to record a win this season and only managed their first try in the 26-17 defeat to Munster in the last round.
The Scots will be a major underdogs for their trip to Watford but the manner of their resounding 45-0 defeat to Sarries in the Pool opener between the sides will still be fresh in the memory.
Edinburgh will also feel they have a point to prove with only seven of their players named in the recent Scotland training squad for the Six Nations by interim coach Scott Johnson.
- Saracens' only defeat in a Round 6 ERC match in the past six seasons was 14-24 at home to ASM Clermont Auvergne in 2010/11.
- This game is scheduled to be Saracens last at Vicarage Road. Their overall record there is P233, W172, D4, L57 whilst their Heineken Cup record at Watford is W14, L5.
- Edinburgh finally scored their first try of the season against Munster after 392 minutes of Heineken Cup action. This is the third longest spell without a try in the history of the competition after Ulster Rugby (465 minutes in 1999-2000) and Swansea (460 minutes in 2001-02).
- Saracens won 45-0 when the two clubs met at Murrayfield in Round 1 - only the third time they had ever been held scoreless at Murrayfield in a competitive match.
- Saracens have managed to evade tackles on just 35 occasions this season; their average of seven defenders beaten per game is a tournament low.