London Irish failed to make home advantage count in Round 3, going down 29-22 at the Madejski Stadium, and that handed all the momentum to Gloucester who then romped to a 47-3 home win over their Premiership rivals.
Nigel Davies' team have proved they can fight on two fronts but will be wary of a French team who ran them close before they won 11-6 in their Round 1 meeting with left wing Ian Clark getting the only try of the match.
- Freddie Burns (67) is the leading points scorer after the opening five rounds of the Amlin Challenge Cup.
- Mont-de-Marsan's victory over Bordeaux-Bègles at the start of December ended a run of six consecutive away defeats in this competition.
- Gloucester's 11 points in their victory over the French side in Round 1 was the fewest they had managed in an Amlin Challenge Cup game since 1996.
- Gloucester have a 70% win rate against French clubs in this competition, their worst rate of any nationality they have faced.