And now Connacht have notched up their first away win in the Heineken Cup by beating tournament new boys Zebre 19-10 in Parma in the opening game of their Pool they will want to build on that win in front of what is expected to be a sell-out crowd in Galway.
Dan Parks took his European points tally through the 550 mark with a match-winning, 14 point contribution on his Heineken Cup debut for his new side.
"We can't wait to play in front of a packed out Sportsground this weekend in our first home Heineken Cup game of this camapign," said try-scorer John Muldoon.
'Quins saw their Heineken Cup dream disappear in the rain of Galway last December but they travel to Ireland as the reigning English champions and on the back of a comfortable 40-13 victory over Biarritz Olympique.
Conor O'Shea's side ran in four tries against last season's Amlin Challenge Cup champions in a comprehensive performance which bodes well for their revenge mission to Ireland.
Nick Evans, Harlequins top points scorer in the Heineken Cup, is still waiting for the opportunity to make it 150 points in this tournament. He needs six more to do so.
Connacht's 9-8 victory over Harlequins in round six last season ended a five game losing run against Premiership opponents.
Quins have lost their last two away matches in Europe.
Quins overall record in Ireland in the Heineken Cup is won 1, lost 5. The only win being 21-15 at Ulster on their first ever visit on 16 October 1996.
The two teams have met on eight previous occasions with Connacht victorious just twice - both at the Sportsground.