But Easterby knows that to stand any chance of erasing their six-try defeat in France from the memory, his Scarlets side need to deal with the threat posed by one of European rugby's iconic players.
Easterby played alongside O'Driscoll in the green of Ireland and is under no illusions of how important the former British & Irish Lions captain is to the reigning Heineken Cup champions.
"He's very important," said Easterby. "He's not getting any younger but certainly not getting any poorer in terms of his attitude and the way he plays the game.
"He still has a real appetite, he's competitive and is someone they look to lead by example. He will have a huge influence on their game".
The last time the two sides met in the Pro12 at the start of the season, the Scarlets emerged as comfortable 45-20 victors at Parc Y Scarlets against a depleted Leinster line-up.
Leinster, after their narrow 9-6 home victory over Exeter Chiefs, will feel they have a point to prove after their last outing when they were pushed all the way by the English outfit in Dublin.
But it is the Scarlets who face a 'must-win' situation in this season's Pool of Death after their one-sided defeat at the hands of Clermont, one of the favourites for this season's tournament.
The Welsh side had wing Morgan Stoddart sent off after a second yellow card offence and played with 14-men for the second half, but the Scarlets know they need to beat Leinster to stand any chance of qualifying for the knockout
Scarlets need 15 more points to collectively score 3000 in the Heineken Cup.
Leinster require 27 points to reach a team total of 3000 in the Heineken Cup.
Jonny Sexton, Leinster's leading points scorer in the Heineken Cup, needs one more point for 350 in this tournament.
Leinster are aiming for their 17th straight victory in the Heineken Cup this weekend.
Scarlets are winless in their last eight matches against Irish opponents in the Heineken Cup since beating Munster 24-15 in the quarter-final at the old Stradey Park on 30 March 2007.