Only Leicester Tigers have managed to successfully defend European club rugby's most coveted title and Leinster are unbeaten in their last 13 tournament matches.
But the fact that they last tasted a Heineken Cup defeat when they went down 20-13 at Clermont in last season's Pool stages will not be lost on Leo Cullen and his team-mates.
Now the clubs go head-to-head again with a prestigious place in the 17th Heineken Cup Final at Twickenham Stadium on Saturday, May 19 at stake against the winner of the Dublin semi-final between Ulster Rugby and Edinburgh Rugby.
Leinster's path to the last four included a clinical 34-3 demolition of Cardiff Blues in the quarter-finals in a match in which Brian O'Driscoll marked his return from injury in typical swashbuckling style.
Ireland's captain is the one who makes the champions tick while full back Rob Kearney is arguably European rugby's form player.
The form player for Clermont at Vicarage Road was outside-half Brock James, called into the action from the replacements bench after just three minutes before proceeding to run the show for the 2010 French champions.
They have a formidable back division that includes French internationals Rougerie, Morgan Parra, Wesley Fofana and Julien Malzieu along with Welsh star Lee Byrne and All Black Sitiveni Sivivatu.
Up front, Nathan Hines - a Heineken Cup winner with Leinster 11 months ago - has been in prime form while the battle at the breakdown promises to be critical, Jamie Heaslip, Sean O'Brien and Julien Bonnaire all world class.
Clermont would love to celebrate their centenary season with a first Heineken Cup crown while Leinster are targeting matching Leicester's feat of back-to-back titles but first there is this intriguing semi-final to decide who marches on to the showpiece event at Twickenham next month.