Stade Francais Paris will be looking to extend their three point lead over French rivals Grenoble at the top of Pool 5 when the tournament resumes in December
The side from the French capital travel to Italy to face bottom-placed side in the Pool, I Cavalieri Prato, and will be hoping to extend their dominance and wrap up their qualification for the quarter-finals.
Stade Francais, with Felipe Contepomi pulling the strings, ground out a narrow 28-25 over Grenoble in a tough encounter in Paris to keep them top of the table and they will know two comprehensive wins will probably guarantee a place in the last eight.
London Welsh, who suffered a humbling 68-19 defeat to Stade Francais in their first taste of European rugby, face a daunting trip to France to face second-placed Grenoble.
Grenoble will be looking for two wins over the English Premiership new boys, London Welsh, to keep the pressure on Stade Francais and themselves in the hunt for the quarter-finals.