Three time European finalists Stade Francais Paris destroyed any hope of a debut win for London Welsh as the visitors were outclassed in every aspect on their way to a 19-68 loss.
And Grenoble marked their return to the Amlin Challenge Cup with a resounding 59-3 victory over struggling I Cavalieri Prato who have only won one Amlin Challenge Cup match in 14 attempts.
The much-anticipated return of Welsh outside-half Gavin Henson did nothing to drive the Exiles forward to victory, despite a strong personal performance, kicking 14 points and playing a part in Daniel George's 30th minute try. The French outfit led 32-16 at the turn, before adding a further 36 points after the break.
Felipe Contepomi claimed 25 points for himself as the world-class kicker reminded everyone that they mean business.SF Paris host Grenoble on October 20th in what will be a much greater challenge.
Fabrice Landreau's Grenoble took just six minutes to open their account as Matthieu Nicolas crossed the line to set the tone for the rest of the match. Seven further tries wrapped up a dismal evening for Prato, their only consolation being a penalty early in the first half.