Michael Cheika's Stade Français Paris will be hoping to strike a blow for the Amlin Challenge Cup when they travel to Heineken Cup semi-finalists ASM Clermont Auvergne in the Top 14 on Saturday.
Stade ran out convincing 37-16 winners at home in the Stade de France earlier in the season and will be seeking to become the first team to win at Stade Marcel Michelin this season.
Stade will face Toulon in the semi-finals of the Amlin Challenge Cup on Friday, 27 April. This weekend Toulon are without their English match-winner Jonny Wilkinson for their trip to Agen.
Wilkinson injured his shoulder in the quarter-final victory over Harlequins and is being rested as a precaution. Aussie legend Matt Giteau takes over at No 10.
Biarrtiz Olympique have managed to climb out of the Top 14 relegation zone with four successive wins and the team that conquered London Wasps in last weekend's Amlin Challenge Cup quarter-finals will be on the road again this weekend.
Not that Dimitri Yachvili, Imanol Harinordoquy and their team mates will have far to go because it is the second leg of the Basque derby at Bayonne. The home side need to win to keep alive their hopes of staying in the Top 14.
The last time the teams met there was a mass brawl on the pitch and Harinordoquy's father came rushing onto the pitch to join in. With so much at stake this weekend for Bayonne, expect more fireworks.
The final Amlin Challenge Cup quarter-finalists, Brive, are also in the mix at the bottom of the Top 14 and face a tough trip to Paris to meet Racing Metro 92. Three of their final four fixtures in the Top 14 are away from home, including trips to the top two teams, Toulouse and ASM Clermont Auvergne, and they also have to travel to Biarritz in the Amlin Challenge Cup semi-finals.
Wher to Find the Amlin Challenge Cup Semi-Finalists This Weekend
Stade Francais (v ASM Clermont Auvergne, away): P. Williams; Sackey, Turinui, Rodriguez Gurrachaga, Camara; Contepomi, Dupuy; Miloud, Sempéré, Slimani, Van Zyl, Papé, Smith, Lyons, Parisse
Replacements: De Malmanche, Roncero, Palmer, Rabadan, Burban, Fillol, Arias, Wright.
Toulon (v Agen, away): Rooney; Lapeyre, Bastareaud, Lavobalavu, Palisson; Giteau, Henjak; Frou, Ivaldi, Kubriashvili, Botha, Shaw, Gunther, Armitage, Van Niekerk.
Replacements: Orioli, Lewis-Roberts, Suta, Fernandez-Lobbe, El Abd, Messina, Cibray, Hayman.
Biarritz Olympique (v Bayonne, away): Balshaw; Bolakoro, Gimenez, Haylett-Petty, Baby; Peyrelongue, Yachvili; Watremez, Heguy, Van Staden, Lund, Taele, Guyot, Harinordoquy, Lakafia
Replacements: Terrain, Kodela, Carizza, Gray, Lesgourgues, Barraque, Burotu, Marconnet
Brive (v Racing Metro 92, away): Spedding; Boussuge, Mignardi, Swanepoel, Cooke; Belie, Figuerola; Kakovin, Lacombe, Barnard, Uys, Mela, Azoulai, Bias, Claassen
Replacements: Ribes, Poirot, Caisso, Ledevedec, Luafutu, Pejoine, Geraghty, Barozzi