Stade Francias Paris, last season's beaten finalists in the Amlin Challenge Cup, will be looking to build on the rich vein of form they have struck in recent weeks in France.
The Paris-based side are on a five-matching winning streak, in all competitions, and will be expected to keep that impressive record when they face Banca Monte Crociati in Italy on Saturday.
The Italian side, who are in only their second season of European rugby, have won only once in their last six games.
Bucharest Wolves v Worcester Warriors
(Sunday December 11)
Worcester Warriors will be determined to get maximum points out of their back-to-back clashes with Romanian outfit, Bucharest Wolves, in the next two rounds of Pool 1.
The English Premiership side, who lie in second place, know they need to keep the pressure on Pool leaders, Stade Francais Paris, if they have any ambitions to qualify for the knockout stages.
The Warriors lost narrowly to the Paris-based outfit in the opening game of the Pool but have since got their campaign back on track with a convincing victory in Italy in the last round.
The Wolves, who beat Italian side Banca Monte Crociati 34-7 in the opening game of the Pool, face a tough task against the Warriors, a side they have never beaten in Europe.