Perpignan will be desperate to get their European campaign back in track when they host Italian side I Cavalieri Prato in their Pool 4 encounter at the Stade Aime Giral on Friday night.
The Catalans, who were comfortably beaten 23-13 by the Newport Gwent Dragons in the last Amlin Challenge Cup game, have a new coaching team of Bernard Goutta and Christophe Manas in charge.
Former coach Jacques Delmas, who saw his side lose five of their last seven games, was dismissed after the defeat in Wales. The French side reached the semi-finals of last season's Heineken Cup and will be looking to achieve the same in the Amlin Challenge Cup.
The Italian outfit, who are only in their second season in the Amlin Challenge Cup are still looking for the second win in Europe, are still looking for a first win in this season's Pool stages.
Exeter Chiefs v Newport Gwent Dragons
(Sunday December 12)
On Sunday the top two in Pool 4 meet at Sandy Park.
The Welsh region travel over the Severn Bridge in confident mood following their opening two victories in the Amlin Challenge Cup this season.
They kicked off their campaign with victory in Italy against I Cavalieri Prato and then retuned to Rodney Parade to beat Perpignan the following weekend.
Their hosts on Sunday sit one-place and just three points below them in the Pool. The English premiership side pushed Perpignan all the way in France in their opening encounter before eventually going down 15 v 12.
They then returned home to beat I Cavalieri Prato which now sets up two cracking games against the Dragons over the next two weekends.