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Bernard Laporte's side lost 28 v 21 to Cardiff Blues in Marseille on that day and their experienced side will be looking to progress through to the knock-out stages once again.
In contrast Italian side Petrarca have never reach the quarter-final stage in their 11 year history in the competition.
Last year saw them record one victory at home to Cetransa El Salador and they will look to key men and former Italian internationals, Warren Spragg and Pietro Travagli for inspiration.
Newcastle Falcons v Lyon
(Saturday November 12 KO 15:00)
Alan Tait's Newcastle side failed to reach the knock-out stage of the Amlin Challenge Cup for only the second time in their history last season and they will look to kick off this season's campaign in style when they welcome European newcomers Lyon to Kingston Park.
The Falcons have reached the semi-final of the tournament four times previously but will have to improve on their recent results, having won only one league encounter this season.
Lyon, under Raphael Saint-Andrew will make their first Amlin Challenge Cup appearance on Saturday and whilst new to the tournament their squad boasts number of household names.
Former Springbok scrum-half Ricky Januarie, Argentina back-row Juan Leguizamon and England full-back Mark Van Gisbergen all play their rugby at the Matmut Stadium.
Lyon have won two of their opening TOP14 matches will look to take the scalp of the English side in their opening clash.
