London Wasps wing, Tom Varndell, will miss his clubs's Amlin Challenge Cup quarter-final against Harlequins on 8 April due to an ankle ligament injury.
Varndell sustained the injury against Gloucester Rugby at Adams Park last weekend. He will undergo surgery and then begin a rehab programme. He is expected to be out of action for up to 12 weeks.
London Wasps Director of Rugby Tony Hanks said: "We are really disappointed for Tom, especially as this season he has been injury-free and has been involved in every single game. His form has been very strong and we will certainly miss him but are confident he will make a full recovery."