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Byrne faces further medical examinations this week to determine the length of the lay-off and the 30-year-old faces a race against time to prove his fitness ahead of Rounds 3 and 4 of the Heineken Cup in December.
The Ospreys travel to Thomond Park on December 12 to line up against double European Champions Munster in the first crucial back-to-back games.
"Lee will be given a specialist opinion this afternoon on whether his injury is treatable with a cast," said Wales physio Mark Davies.
"If that is the case rather than surgery he will have an outside chance of being back for the All Blacks game."
