Stade Francais travel to Headlingly Carnegie to face Leeds in Pool Four this weekend.
Leeds will be hoping the proposition of playing the 2002 and 2005 finalists will raise the levels of their performance.
Director of Rugby Andy Key said: "Naturally we are all very excited about this game,. No matter who you are you want to test yourself against the very best and Stade are unquestionably - and regularly - one of the best sides in Europe."
Bucharest Oaks host Crociati Rugby at Acrul de Triumf.
The Romanians's will aim to gain victory in their opening home game of the competition and in the club's history.
Both teams will want to get out of the blocks after suffering defeat in the opening fixtures.