Biarritz Olympique will hope to bounce back into Pool 3 contention after their opening defeat to Harlequins when they host Italian new boys Zebre on their home patch on Saturday night.
The reigning Amlin Challenge Cup champions suffered a 40-13 defeat to Harlequins, the reigning English champions, in London last weekend.
The Basque outfit have a formidable record at the Stade Aguilera, having lost only four of their 41 Heineken Cup games at home, and former England full back Iain Balshaw has become a firm favourite with their passionate supporters.
Zebre, who are in their first season of European rugby, are still looking for their first win and points in the Heineken Cup.
Zebre, the new Italian franchise, will be hoping they can stun the rugby world in the same manner as the team they replaced did against Biarritz.
Aironi, who were wound up last season after two years and were replaced by Zebre in this season's Pro12, famously beat Biarritz 28-27 at home in their first campaign in 2011.
The victory over Biarritz stunned European rugby and was Aironi's first historic victory as a professional outfit. Zebre would love to emulate Aironi's feat.
Match Facts
Zebre back row Filippo Ferrarini was one of six players to produce three turnovers won in the opening round.
Biarritz conceded 40 points in Europe last weekend for the first time since 2008, when they lost 45-16 at Saracens, their heaviest every European defeat.
Zebre are yet to taste victory this season having lost all five of their league fixtures and their Heineken Cup opener last weekend.
The Italian side have averaged a tally of 13 points scored and 31 conceded per game this season.
At home, Biarritz boast an 87% win rate from 45 matches in their history. They have won 86% of their 14 matches against Italian opponents overall.