Harlequins seized the initiative in Pool 3 with a rousing victory over Biarritz Olympique at The Twickenham Stoop.
English champions Quins produced a devastating second-half display to claim what could prove to be a crucial bonus-point over their French rivals.
Danny Care crossed in the first half only for Arnaud Heguy and the boot of Julien Peyrelongue to level the scores at 13-13 at half-time.
But Quins stepped on the gas after the break as Rob Buchanan, Jordan Turner-Hall and Steb Stegmann ensured maximum points.
England scrum-half Care handed the hosts a perfect start when he raced on to Chris Robshaw's off-load from a lineout and stepped through to score in the seventh minute.
But Quins suffered a blow when fly-half Nick Evans limped off with an ankle injury.
That opened the door for summer signing Ben Botica, son of All Black legend Frano, to get his first taste of Heineken Cup rugby.
And the New Zealander wasted no time in making his mark, kicking his first effort just minutes after taking the field.
Biarritz hit back with a well-worked driving maul that saw hooker Hugey touch down and Peyrelongue levelled the scores.
Hugey's opposite number Buchanan responded with a score of his own just four minutes into the second half, Robshaw again providing the scoring pass.
Turner-Hall then finished a sweeping attack sparked by Care's audacious break through the middle of the field and replacement Stegmann capped an impressive display with the bonus-point score two minutes from time.