Clermont Auvergne bounced back from defeat in Round 1 to comfortably beat Italian side Aironi 54 v 3 on Friday evening.
Lee Byrne opened the scoring, the Welsh full-back touching down after just ten minutes at the Stade Stade Marcel Michelin. Scrum-half Morgan Parra added the conversion
Luciano Orquera grabbed a penalty for the visitors after 13 minutes but the remaining first period was all about the hosts who scored two further tries through Gerhard Vosloo and Brock James.
Parra again was on form with the boot taking the scores to 21 v 3 at the break.
The hosts then wrapped up the crucial try-scoring bonus point with Julien Bonnaire touching down after 50minutes.
Flanker Julien Bardy was next on the score-sheet for Clermont's fifth try and Brock James added the conversion.
Jean-Marcel Buttin, Wesley Fofana and Julien Malzieu all scored further tries in a comfortable victory for Jean-Marc Lhermet's try.