French rugby's new boys, Lyon Rugby, need to come away with all the spoils to keep their Amlin Challenge Cup hopes alive when they travel to Italy to face Petrarca Rugby.
The French side, who were promoted to the Top 14 in the summer and are in their first season of European rugby, recorded a 54-20 victory at home against the Italian side last weekend.
Lyon are currently third in Pool 2 and are behind leaders Newcastle and fellow French side Toulon. Petrarca are still looking for their first win in this season's Amlin Challenge Cup.
Toulon v Newcastle Falcons
(Saturday December 17)
Toulon will be looking for revenge when they host Premiership outfit Newcastle Falcons in the return game of the 'double-header' between the two sides at the Stade Felix-Mayol.
The French side suffered a 6-3 defeat to the Falcons last week but need a victory over the English side to keep their hopes of a quarter-finals place in this season's tournament alive.
Toulon, who were beaten finalists in the Amlin Challenge Cup in 2010, know a win in this top of the table clash will put the French side in pole position for the final two games in Pool 2.