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The French club, who have signed Wales fly half ace Stephen Jones from next season, will try to limit the chances they give current No 10 Burke to punish them with the boot while wary of the hard-running Greenwood in the centre.
"Harlequins have an excellent kicker in their number 10, a world champion at inside centre and they recently turned the tide against Bath which shows they dig their heels in right up to the final whistle," said coach Alain Hyardet.
"That is what we will have to do if we want to win this match. In our other matches in England this season, we performed well for 60 minutes but this time it has to be 80.
"The game will be won on details - whoever concedes the least amount of penalties and keeps the ball will be under less pressure and has a good chance of winning the match - and the title.
"We have been playing a series of competitive matches in the play-down stage of the French championship which was good preparation for the Parker Pen Challenge Cup final.
"Each time we have crossed the channel so far this season we have played well but Harlequins will be a difficult match. It's sink or swim on one knock-out match this time and we are playing in the opposition's backyard so with the support they will have, it's like one playing against one and a half!"
"And we have had a very difficult week because we have had three games - and Olivier Magne left the field against Montauban with a thigh strain. But, other than that, we don't have too many injury worries.
"It is going to be a very important occasion for us on Saturday and we know that Harlequins will be a very strong side. We have lost each time we have played in England this season - at Newcastle, Saracens and Bath - but we have always been able to turn things around back at our own stadium.
"As most people already know, it has not been a great season for us domestically - we had seven players in World Cup squad and that put pressure on us in the first part of the French Championship. That stage of the Championship is always very defensive we have been chasing our tails for the remainder of the tournament so this final comes at a good time for us.
"Finals are different to two-leg matches - we will try and forget about what is going to be a hostile environment and play for the ultimate prize of reaching the Heineken Cup. It is so important for us to qualify for the Heineken Cup.
"Toulouse, Montpellier and ourselves are all involved in European finals this weekend and it would be great for French rugby if we could win the three trophies - but we know exactly how difficult that is going to be."
