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Munster won the quarter-final meetings in 2000 and 2002 by 27-10 and 16-14 margins, the Paris club triumphing 16-15 in the 2001 semi-final in Lille.
"It's very tough to play in Munster - it always is," said international prop Pieter de Villiers. "They are a very physical side and we have to take the game to them and match them physically. I think if we do that, we could have a chance of coming away from Ireland with a result for the first time.
"It's all or nothing at this stage. We don't have much realistic chance of getting to the play-offs of the French Championships - which means that our only chance of qualifying for next season's Heineken Cup is to win it.
"To qualify is very important, which puts more pressure on our shoulders, but at the same time you could say we've got nothing to lose and everything to play for.
"We have played Munster twice in quarter-finals and lost on both occasions so hopefully this will be third time lucky. We've had a difficult season and it's hard to explain why we haven't played well at certain times - rugby is not a science.
"Having said that, we have done well in our Heineken Cup matches and there's no reason why we can't go over there and produce the goods on Saturday."
