Leonessa's Italian outside half Rima Wakarua will be watching from the sidelines as his team try to bridge the 33-point gap on French outfit Montpellier, that exists from their first leg defeat in the Parker Pen Shield semi-final.
Wakakrua was able to kick only one conversion in his side's 45-12 defeat at the Sabathe Ground, but is unavailable through injury and has been replaced by Alessandro Buso.
His half back partner Meyer grabbed two tries for the visitors, who conceded seven tries to the home side.
Full back David Bortolussi was one of the try scorers, and he also kicked five conversions. He will be looking for more points in the second leg.
Montpellier have made eight changes form the first leg. With Five of the changes coming up front, with the Georgian international pair of Soso Nikoloaenko and Mamuka Magrakvelidze coming into the pack.
Leonessa: F Zitelli; V Becalli, M Colosio, L Thomas, F Casagrande; A Buso, B Meyer; I Rouyet, D Porrino, R Mattei, E Podesta, M Vella, C Bonetti, J Ricciardo, G Gonzalez
Replacements: P Coletti, A Marengoni, R Denhardt, D Kingi, A Cavalleri, M Madigan, E Ferdezioni,
Montpellier: D Bortolussi; S Jouve, F Charrier, B Tissot, A Rossi; J Valls, J Tomas; P Tacchella, L Armand, S Nikolaenko, J Caudullo, M Magrakvelidze, S Welch, C Mathieu, O Dussant
Replacements: J Leothier, C Baiocco, J Daniell, M MacUrdy, A Stoica, S Buada, D Navizet,
Referee: David Changleng (Scotland)