Three are through from three different nations and five more - the other three Pool winners and the two best runners-up - will qualify at the weekend.
The Heineken Cup 2009 quarter-finals are taking shape but with five prestigious spots still to be claimed, Round 6 promises to be another weekend of high drama.
The three qualifiers so far are:
MUNSTER - The defending champions have won through to the knock-out stages for the 11th successive season.
CARDIFF BLUES - The only team left with a 100 per cent record after a fifth win earned them a last eight place for the seventh time.
HARLEQUINS - Lost in Belfast but won a quarter-final place for the first time since 1998 when the Scarlets knocked out Stade Français Paris.
Now the race is on to join these three qualifiers with the prospect of things going all the way to the final whistle in a number of matches, the two matches in each Pool kicking-off simultaneously.
In Pool 2 Leinster and London Wasps are both on 16 points with Leinster holding a slight advantage with a 6-4 match points return from the two matches between the sides. Leinster take on Edinburgh at the RDS and Wasps travel to France to meet Castres Olympique at Stade Pierre-Antoine
In Pool 3 leaders Leicester Tigers travel to the Liberty Stadium to meet the Ospreys with a four-point cushion and a 4-1 match points advantage from their Round 1 contest. That one will be settled on Saturday evening.
In Pool 5 it is another potential winner-takes-all showdown with Bath Rugby on 19 points, one ahead of visitors Toulouse, with the French club ahead 4-1 on match points from another Round 1 tight finish. This Sunday shoot-out will end the Pool action of the 14th Heineken Cup season.