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Commentator Michael Corcoran, who will be covering his 106th Heineken Cup game, will be joined by former Leinster and Ireland prop Emmett Byrne as Michael Cheika's side aim to become only the second side to win at the Stade Armandie this season.
Munster's Pool 4 game at Thomond Park at 5.30pm also features on the programme, Gary Moran and Ciaran Fitzgerald will describe the action as Declan Kidney's side aim to maintain their unbeaten start to the campaign.
Kick off is at 3.30pm Irish time for Agen v Leinster and 5.30pm for Munster Cardiff and both matches will be available on FM, 567 MW and LW 252.
The games will also be streamed on www.rte.ie/sport and on www.ercrugby.com click on audio broadcast and scroll to live audio broadcasts.
