Clermont Auvergne outside half Stephen Jones is set to miss this weekend's Heineken Cup Round 5 match against the Ospreys at Liberty Stadium after failing a fitness test
Jones had suffered this season with a persistent ankle injury, and despite intensive treatment to ensure his availability, Jones will not make the 22.
The British and Irish Lions and Wales No 10 will play his rugby in his native Wales next season. Earlier this week he confirmed he will be returning to Llanelli to play for the Scarlets after a successful two-year spell at Clermont.
Also missing through injury from the visitors' squad are wing Aurelien Rougerie and scrum-half Pierre Mignoni.
Both teams are out of contention for quarter-final qualification but the Ospreys will be desperate to arrest an alarming four-match losing run, including dismal defeats to the Dragons and the Blues over the Christmas period.
The Celtic League champions will be looking to exact revenge on Clermont Auvergne, who won the reverse fixture in France 34-14 back in October.
Finals Edition: Listen to the best guide to the European Rugby Cup Finals weekend in Dublin, which sees Leinster Rugby take on Stade Francais Paris at the RDS on Friday night in the Amlin Challenge Cup Final and then ASM Clermont Auvergne tackle Toulon in an all-French affair at the Aviva Stadium on Saturday.