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At Sixways Stadium, Shane Drahm's 20 points inspired the Warriors to a valuable 30-20 victory over Connacht.
The victory gives Worcester the lead in Pool 5, but they face a tricky trip to Connacht next weekend before they start thinking about the quarter-finals.
The Warriors struck the opening blow with a try to fullback Nicolas Le Roux, but the 17th-minute sin-binning of skipper Pat Sanderson proved costly. Connacht fly-half David Slemen converted the penalty and then added the extras to centre Keith Matthews' try.
Drahm converted his own try to give the home side a 14-10 lead at the break, and the Warriors needed the Australian's reliable boot to keep their noses in front.
Three second-half penalty goals from Drahm cancelled a Matt Mostyn try, and a last-minute try to backrower Drew Hickey sealed the victory.
Northampton fullback Bruce Reihana was among the try-scorers in the Saints' 32-20 home win over Narbonne, and the Kiwi's 12 points with the boot proved the difference on the day.
Reihana and backrowers Dan Browne and Sam Harding gave Saints a handy 20-7 lead at halftime, but Narbonne's gritty comeback will sound the alarm bells ahead of the English club's trip to France next weekend.
