Sale Sharks have suffered a triple injury blow ahead of the European Challenge Cup final later this month.
Wing Steve Hanley and back-row forwards Jason White and John Carter will all miss the May 21 appointment with French club Pau at Oxford United's Kassam Stadium.
Prolific try-scorer Hanley faces a four-month absence after suffering a double fracture of his right leg during Sharks' Zurich Premiership play-off defeat against Wasps on Saturday.
Hanley was hurt late in the game as Sale slipped to a 43-22 defeat, and x-rays have now confirmed the injury's seriousness. Hanley's obvious replacement, former Northampton wing Oriol Ripol, is not registered for European competitions this season, so Sale's options are now likely to include centre John Payne or England Under-21 scrum-half Ben Foden.
White and Carter were injured in the same match, with Scottish international White being ruled out for five to six weeks due to a broken thumb. Carter, meanwhile, suffered a dislocated shoulder, and like Hanley, is not expected to return until September.
"I am gutted for all three players, who had played such prominent roles in the games which took us to the European Challenge Cup final,'' said Sharks head coach Kingsley Jones.
There was encouraging news surrounding Sharks' England fly-half Charlie Hodgson, though. Hodgson, who will tour New Zealand with the Lions this summer, has been given the all-clear following a clash of heads with Wasps lock Simon Shaw.