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The Sharks, the 2002 and 2005 winners, are joined by Harlequins, the 2001 and 2004 champions, in bidding to make it three titles with the London club travelling to Bayonne for their opening clash on Sunday, 10 October.
Bourgoin and Gloucester Rugby are also past winners of a tournament which will again see the five Pool winners and three of the Heineken Cup Pool runners-up contesting the knock-out stages in 2011.
Tournament newcomers are Premiership club Exeter Chiefs and Italian club Cavalieri Prato with Rugby Parma now operating as Crociati Rugby.
AMLIN CHALLENGE CUP 2010 / 2011 FIXTURES
(All kick-offs LOCAL time)
ROUND 1
THURSDAY 7 OCTOBER, 2010
Pool 3 Newcastle Falcons v Bourgoin 19.45 Sky Sports
Pool 4 Stade Français Paris v Crociati Rugby 20.45 Eurosport France
FRIDAY 8 OCTOBER, 2010
Pool 2 Sale Sharks v Cetransa El Salvador 19.45
Pool 2 Brive v Petrarca Rugby 20.00
Pool 5 Agen v Gloucester Rugby 18.30 Eurosport France
SATURDAY 9 OCTOBER, 2010
Pool 1 Cavalieri Prato v Connacht Rugby 15.00
Pool 3 Exeter Chiefs v Montpellier 15.00
Pool 4 Bucuresti Oaks v Leeds Carnegie 15.00
Pool 5 Rugby Rovigo v La Rochelle 15.00
SUNDAY 10 OCTOBER, 2010
Pool 1 Bayonne v Harlequins 18.45 FR4
ROUND 2
THURSDAY 14 OCTOBER, 2010
Pool 3 Montpellier v Newcastle Falcons 20.45 Eurosport France
FRIDAY 15 OCTOBER, 2010
Pool 1 Connacht Rugby v Bayonne 19.00
Pool 3 Bourgoin v Exeter Chiefs 19.30
SATURDAY 16 OCTOBER, 2010
Pool 1 Harlequins v Cavalieri Prato 15.00
Pool 2 Cetransa El Salvador v Brive 16.30
Pool 2 Petrarca Rugby v Sale Sharks 15.00
Pool 4 Bucuresti Oaks v Crociati Rugby 15.00
Pool 5 La Rochelle v Agen 20.45 Eurosport France
Pool 5 Gloucester Rugby v Rugby Rovigo 15.00
SUNDAY 17 OCTOBER, 2010
Pool 4 Leeds Carnegie v Stade Français Paris 17.45 Sky Sports
ROUND 3
THURSDAY 9 DECEMBER, 2010
Pool 3 Montpellier v Bourgoin 20.45 Eurosport France
SATURDAY 11 DECEMBER, 2010
Pool 2 Brive v Sale Sharks 20.45 FR4
Pool 2 Petrarca Rugby v Cetransa El Salvador 15.00
Pool 3 Exeter Chiefs v Newcastle Falcons 15.00
Pool 4 Bucuresti Oaks v Stade Français Paris 15.00
Pool 5 La Rochelle v Gloucester Rugby 18.30
Pool 5 Rugby Rovigo v Agen 15.00
SUNDAY 12 DECEMBER, 2010
Pool 1 Bayonne v Cavalieri Prato 18.45 Eurosport France
Pool 1 Harlequins v Connacht Rugby 17.45 Sky Sports
Pool 4 Leeds Carnegie v Crociati Rugby 15.00
ROUND 4
THURSDAY 16 DECEMBER, 2010
Pool 4 Stade Français Paris v Bucuresti Oaks 20.45 Eurosport France
FRIDAY 17 DECEMBER, 2010
Pool 1 Connacht Rugby v Harlequins 19.00
SATURDAY 18 DECEMBER, 2010
Pool 1 Cavalieri Prato v Bayonne 15.00
Pool 3 Bourgoin v Montpellier 20.45 Eurosport France
Pool 5 Agen v Rugby Rovigo 14.30
SUNDAY 19 DECEMBER, 2010
Pool 2 Sale Sharks v Brive 15.00
Pool 2 Cetransa El Salvador v Petrarca Rugby 12.30
Pool 3 Newcastle Falcons v Exeter Chiefs 15.00
Pool 4 Crociati Rugby v Leeds Carnegie 14.30
Pool 5 Gloucester Rugby v La Rochelle 17.45 Sky Sports
ROUND 5
13 / 14 / 15 / 16 JANUARY, 2011
Pool 1 Cavalieri Prato v Harlequins
Pool 1 Bayonne v Connacht Rugby
Pool 2 Sale Sharks v Petrarca Rugby
Pool 2 Brive v Cetransa El Salvador
Pool 3 Newcastle Falcons v Montpellier
Pool 3 Exeter Chiefs v Bourgoin
Pool 4 Stade Français Paris v Leeds Carnegie
Pool 4 Crociati Rugby v Bucuresti Oaks
Pool 5 Agen v La Rochelle
Pool 5 Rugby Rovigo v Gloucester Rugby
ROUND 6
20 / 21 / 22 / 23 JANUARY, 2011
Pool 1 Harlequins v Bayonne
Pool 1 Connacht Rugby v Cavalieri Prato
Pool 2 Petrarca Rugby v Brive
Pool 2 Cetransa El Salvador v Sale Sharks
Pool 3 Montpellier v Exeter Chiefs
Pool 3 Bourgoin v Newcastle Falcons
Pool 4 Leeds Carnegie v Bucuresti Oaks
Pool 4 Crociati Rugby v Stade Français Paris
Pool 5 La Rochelle v Rugby Rovigo
Pool 5 Gloucester Rugby v Agen
QUARTER-FINALS
7 / 8 / 9 / 10 APRIL, 2011
SEMI-FINALS
30 APRIL / 1 MAY, 2011
15th AMLIN CHALLENGE CUP FINAL
20 / 21 / 22 MAY, 2011
